Micro fluidic components for innovative analysis platform
Within the EU-project CAJAL4EU an innovative analysis platform for in-vitro diagnosis with a total analysis time of less than one hour will be developed.
The ENIAC-project called "CAJAL4EU" is financially supported with 1.8 million Euro by the Federal Ministery of Education and Research under the theme High-Tech-Strategy 2020 "Informations- und Kommunikationstechnologie 2020" (IKT 2020).
A total of 25 partners from 8 European countries are working on the realization and optimization of novel complementary metal oxide semiconductor (CMOS) biosensors, the development of micro fluidic Lab-on-a-Chip (LoC)-Systems for sample loading and preparation, as well as the fluidic, mechanical and electrical integration of silicon sensors into the LoC environment.
By using strongly miniaturized biosensors with integrated amplifier circuits a considerably higher sensitivity – compared to conventional detection principles – can be realized. The increase in sensitivity and the combination with the automated microfluidic sample preparation allows a reduction of analysis time to less than one hour. Thus the system is particularly suitable for operation in pointof-care diagnosis.
The right treatment at the right time with Point-of-Care-Diagnosis
First of all CAJAL4EU focuses on diagnostic applications in the area of infectious diseases (mainly respiratory diseases) and cardiovascular diseases (protein-biomarker). Finally a strong platformoriented solution shall be developed which can easily be expanded for further applications and allows a multi-parameter analysis.
Fluidic Key Technologies
IMM contributes to CAJAL4EU in the issues of sample loading/preparation as well as the development of fluidic key technologies for process control (actuating elements and sensor technology) and reagent storage. IMMs aim is to contribute to the conception of LoC systems by providing important solutions for micro fluidic components (pumps, valves and sensors for temperature and process control). This includes the manufacturing of highly integrated silicon sensors which can be controlled by an intelligent micro fluidic system.
Contact: Knut Welzel, Fluidics and Simulation Department,
Phone: +49 6131/990 431